Viral population dynamics and virulence thresholds
نویسندگان
چکیده
منابع مشابه
Mechanisms controlling virulence thresholds of mixed viral populations.
The propensity of RNA viruses to revert attenuating mutations contributes to disease and complicates vaccine development. Despite the presence of virulent revertant viruses in some live-attenuated vaccines, disease from vaccination is rare. This suggests that in mixed viral populations, attenuated viruses may limit the pathogenesis of virulent viruses, thus establishing a virulence threshold. H...
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ژورنال
عنوان ژورنال: Current Opinion in Microbiology
سال: 2012
ISSN: 1369-5274
DOI: 10.1016/j.mib.2012.05.007